Sexual health

Sexual side-effects of medicines: what to do

Some antidepressants, antipsychotics and BP medicines can affect desire, erection or ejaculation. Why you should not stop suddenly and what options exist.

Dr. Kuldeep Budania, MBBS, MD Psychiatry

Updated 11 October 2026 · 3 min read

Sexual side-effects are a common reason people stop their medicines without telling the doctor — which can lead to relapse.

These effects can usually be managed once discussed openly.

Key concepts

  • Tell your doctor — it is a routine question
  • Options include dose change, switching or timing adjustments
  • The illness itself can also reduce sexual function

Symptoms and signs

  • Reduced desire
  • Erectile difficulty or vaginal dryness
  • Delayed or absent orgasm/ejaculation

Causes

  • Medicine effects on brain chemicals and hormones
  • Effects on blood flow (some BP medicines)
  • Underlying depression, diabetes or anxiety

Risk factors

  • Higher doses
  • Multiple medicines
  • Alcohol use

Evidence-based management

  • Do not stop medicines on your own
  • Doctor may lower the dose or switch to an option with fewer sexual effects
  • Treat co-existing issues (diabetes, low mood)
  • Specific treatments for ED or dryness when appropriate

When to seek professional help

  • Side-effects making you want to stop treatment
  • New sexual problems after starting a medicine
  • A private video consultation is available in Hindi or English; your partner can join if you wish

Frequently asked questions

Will the problem go away when I stop the medicine?

Usually it improves, but stopping without a plan risks the original illness returning.

Is it embarrassing to ask?

Not at all. Doctors ask about it routinely because it affects treatment success.

Medical references

Guidelines and official sources used for this article.

  1. Depression in adults: treatment and management (NG222). National Institute for Health and Care Excellence (NICE), UK, 2022.
  2. Erectile Dysfunction: AUA Guideline. American Urological Association, 2018.
Author
Dr. Kuldeep Budania, MBBS, MD Psychiatry
Medical reviewer
Dr. Kuldeep Budania, MD Psychiatry
Last reviewed

This article is for general information and is not a substitute for personal medical advice.

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